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UEFA Champions League – Matchday 3 Predictions and Best Bets

  • Writer: 365Advent Team
    365Advent Team
  • Oct 21
  • 3 min read
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The UEFA Champions League group stage is reaching a crucial point, and Matchday 3 promises fireworks across Europe. With several top clashes on the schedule, fans can expect drama, goals, and plenty of betting opportunities. Here’s a full breakdown of the fixtures, predicted scores, and best bets.

Tuesday, 21 October 2025

Barcelona vs Olympiacos

Barcelona’s attacking strength at the Camp Nou should be too much for Olympiacos, although the Greek side could still make things difficult early on.

Predicted score: Barcelona 3–0 Olympiacos Best bet: Barcelona -1.5 handicap

Kairat Almaty vs Pafos

Kairat will look to capitalize on their home advantage in Kazakhstan, but Pafos are well-organized defensively. Expect a cagey contest.

Predicted score: Kairat Almaty 1–1 Pafos Best bet: Under 2.5 goals

Arsenal vs Atlético Madrid

One of the standout fixtures of the week. Arsenal’s high press could struggle against Atlético’s compact defense and countering power. A tactical chess match awaits.

Predicted score: Arsenal 1–1 Atlético Madrid Best bet: Draw or Under 2.5 goals

Leverkusen vs Paris Saint-Germain

Leverkusen’s fluid attack meets PSG’s individual brilliance. Expect end-to-end football and goals on both sides.

Predicted score: Leverkusen 2–2 PSG Best bet: Both teams to score + Over 2.5 goals

Villarreal vs Manchester City

City remain heavy favorites, but Villarreal’s disciplined structure could frustrate them early. Still, Pep’s side should find a way through.

Predicted score: Villarreal 1–3 Manchester City Best bet: Manchester City to win + Over 2.5 goals

PSV Eindhoven vs Napoli

Both teams are known for attacking football and dynamic transitions. Expect plenty of chances and a fast-paced affair.

Predicted score: PSV 2–2 Napoli Best bet: Both teams to score

Copenhagen vs Borussia Dortmund

Copenhagen are always strong at home, but Dortmund’s attacking options make them hard to stop. A narrow away win looks likely.

Predicted score: Copenhagen 1–2 Borussia Dortmund Best bet: Borussia Dortmund to win

Union SG vs Inter Milan

Union SG’s high energy might cause problems early, but Inter’s quality in midfield should see them through comfortably.

Predicted score: Union SG 0–2 Inter Milan Best bet: Inter Milan to win to nil

Newcastle United vs Benfica

St. James’ Park will be electric as Newcastle look to continue their European push. Benfica’s experience might make this closer than expected.

Predicted score: Newcastle 2–1 Benfica Best bet: Newcastle to win or Both teams to score

Wednesday, 22 October 2025

Galatasaray vs Bodø/Glimt

A lively game awaits in Istanbul. Galatasaray’s attacking power should be enough, though Bodø/Glimt’s pressing may lead to chances.

Predicted score: Galatasaray 2–1 Bodø/Glimt Best bet: Both teams to score

Athletic Club vs Qarabağ

Athletic Club’s intensity and home crowd should overwhelm Qarabağ. Expect a solid, professional win.

Predicted score: Athletic Club 2–0 Qarabağ Best bet: Athletic Club to win to nil

Chelsea vs Ajax

Chelsea look rejuvenated under pressure and could outclass Ajax in London. The Dutch side’s defense has been inconsistent.

Predicted score: Chelsea 3–1 Ajax Best bet: Chelsea to win + Over 2.5 goals

Atalanta vs Slavia Praha

Expect fireworks in Bergamo. Both teams play positive football and leave space at the back.

Predicted score: Atalanta 2–1 Slavia Praha Best bet: Both teams to score

Frankfurt vs Liverpool

A high-tempo, attacking clash is almost guaranteed. Liverpool’s attacking trio should make the difference in an open match.

Predicted score: Liverpool 3–2 Frankfurt Best bet: Both teams to score + Over 2.5 goals

Sporting CP vs Marseille

Sporting have been solid at home, while Marseille remain unpredictable. Expect a tight contest with a narrow home win.

Predicted score: Sporting CP 2–1 Marseille Best bet: Sporting CP to win or draw (Double Chance)

Monaco vs Tottenham

Tottenham’s counter-attacks could hurt Monaco, but the French side are tough to beat at home. Expect a close, tactical draw.

Predicted score: Monaco 1–1 Tottenham Best bet: Draw or Under 2.5 goals

Real Madrid vs Juventus

A European classic. Real Madrid’s depth and home advantage should be enough to see off Juventus, who may struggle to create.

Predicted score: Real Madrid 2–0 Juventus Best bet: Real Madrid to win to nil

Bayern Munich vs Club Brugge

Bayern’s relentless attack and home dominance make them clear favorites. Expect a comfortable win for the German giants.

Predicted score: Bayern Munich 3–0 Club Brugge Best bet: Bayern Munich -1.5 handicap

Final Thoughts

Matchday 3 delivers a stacked lineup featuring some of Europe’s biggest clubs and high-stakes encounters. With goals expected across several fixtures, particularly Liverpool vs Frankfurt, Leverkusen vs PSG, and PSV vs Napoli, this round could be a treat for fans and bettors alike.

Stay tuned for our post-match breakdown and updated odds comparison insights as the Champions League drama continues.

 
 
 

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