UEFA Champions League – Matchday 3 Predictions and Best Bets
- 365Advent Team

- Oct 21
- 3 min read

The UEFA Champions League group stage is reaching a crucial point, and Matchday 3 promises fireworks across Europe. With several top clashes on the schedule, fans can expect drama, goals, and plenty of betting opportunities. Here’s a full breakdown of the fixtures, predicted scores, and best bets.
Tuesday, 21 October 2025
Barcelona vs Olympiacos
Barcelona’s attacking strength at the Camp Nou should be too much for Olympiacos, although the Greek side could still make things difficult early on.
Predicted score: Barcelona 3–0 Olympiacos
Best bet: Barcelona -1.5 handicap
Kairat Almaty vs Pafos
Kairat will look to capitalize on their home advantage in Kazakhstan, but Pafos are well-organized defensively. Expect a cagey contest.
Predicted score: Kairat Almaty 1–1 Pafos
Best bet: Under 2.5 goals
Arsenal vs Atlético Madrid
One of the standout fixtures of the week. Arsenal’s high press could struggle against Atlético’s compact defense and countering power. A tactical chess match awaits.
Predicted score: Arsenal 1–1 Atlético Madrid
Best bet: Draw or Under 2.5 goals
Leverkusen vs Paris Saint-Germain
Leverkusen’s fluid attack meets PSG’s individual brilliance. Expect end-to-end football and goals on both sides.
Predicted score: Leverkusen 2–2 PSG
Best bet: Both teams to score + Over 2.5 goals
Villarreal vs Manchester City
City remain heavy favorites, but Villarreal’s disciplined structure could frustrate them early. Still, Pep’s side should find a way through.
Predicted score: Villarreal 1–3 Manchester City
Best bet: Manchester City to win + Over 2.5 goals
PSV Eindhoven vs Napoli
Both teams are known for attacking football and dynamic transitions. Expect plenty of chances and a fast-paced affair.
Predicted score: PSV 2–2 Napoli
Best bet: Both teams to score
Copenhagen vs Borussia Dortmund
Copenhagen are always strong at home, but Dortmund’s attacking options make them hard to stop. A narrow away win looks likely.
Predicted score: Copenhagen 1–2 Borussia Dortmund
Best bet: Borussia Dortmund to win
Union SG vs Inter Milan
Union SG’s high energy might cause problems early, but Inter’s quality in midfield should see them through comfortably.
Predicted score: Union SG 0–2 Inter Milan
Best bet: Inter Milan to win to nil
Newcastle United vs Benfica
St. James’ Park will be electric as Newcastle look to continue their European push. Benfica’s experience might make this closer than expected.
Predicted score: Newcastle 2–1 Benfica
Best bet: Newcastle to win or Both teams to score
Wednesday, 22 October 2025
Galatasaray vs Bodø/Glimt
A lively game awaits in Istanbul. Galatasaray’s attacking power should be enough, though Bodø/Glimt’s pressing may lead to chances.
Predicted score: Galatasaray 2–1 Bodø/Glimt
Best bet: Both teams to score
Athletic Club vs Qarabağ
Athletic Club’s intensity and home crowd should overwhelm Qarabağ. Expect a solid, professional win.
Predicted score: Athletic Club 2–0 Qarabağ
Best bet: Athletic Club to win to nil
Chelsea vs Ajax
Chelsea look rejuvenated under pressure and could outclass Ajax in London. The Dutch side’s defense has been inconsistent.
Predicted score: Chelsea 3–1 Ajax
Best bet: Chelsea to win + Over 2.5 goals
Atalanta vs Slavia Praha
Expect fireworks in Bergamo. Both teams play positive football and leave space at the back.
Predicted score: Atalanta 2–1 Slavia Praha
Best bet: Both teams to score
Frankfurt vs Liverpool
A high-tempo, attacking clash is almost guaranteed. Liverpool’s attacking trio should make the difference in an open match.
Predicted score: Liverpool 3–2 Frankfurt
Best bet: Both teams to score + Over 2.5 goals
Sporting CP vs Marseille
Sporting have been solid at home, while Marseille remain unpredictable. Expect a tight contest with a narrow home win.
Predicted score: Sporting CP 2–1 Marseille
Best bet: Sporting CP to win or draw (Double Chance)
Monaco vs Tottenham
Tottenham’s counter-attacks could hurt Monaco, but the French side are tough to beat at home. Expect a close, tactical draw.
Predicted score: Monaco 1–1 Tottenham
Best bet: Draw or Under 2.5 goals
Real Madrid vs Juventus
A European classic. Real Madrid’s depth and home advantage should be enough to see off Juventus, who may struggle to create.
Predicted score: Real Madrid 2–0 Juventus
Best bet: Real Madrid to win to nil
Bayern Munich vs Club Brugge
Bayern’s relentless attack and home dominance make them clear favorites. Expect a comfortable win for the German giants.
Predicted score: Bayern Munich 3–0 Club Brugge
Best bet: Bayern Munich -1.5 handicap
Final Thoughts
Matchday 3 delivers a stacked lineup featuring some of Europe’s biggest clubs and high-stakes encounters. With goals expected across several fixtures, particularly Liverpool vs Frankfurt, Leverkusen vs PSG, and PSV vs Napoli, this round could be a treat for fans and bettors alike.
Stay tuned for our post-match breakdown and updated odds comparison insights as the Champions League drama continues.
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